What to do with tongue cancer?

Definition: What is tongue cancer?

Tongue cancer (technical term: tongue carcinoma) is a malignant tumour in the tongue area and falls into the category of oral cavity cancer. Tongue cancer is particularly common on the front two-thirds of the tongue - either on the side, directly on the tongue or on the underside of the tongue. Tumours under the tongue are usually cancer of the floor of the mouth and not tongue cancer. If tongue cancer develops far back on the last third of the tongue, it can also be referred to as throat cancer.

In around 95 per cent of cases, tongue cancer originates from the uppermost layer of the oral mucosa, the squamous epithelium. Tongue cancer can metastasise to the lymph nodes and also spread to other organs via the bloodstream, where it can impair vital functions.

Prognosis: Can tongue cancer be cured?

In the case of cancer, life expectancy is usually expressed as a "five-year survival rate". This value indicates the percentage of patients who are still alive five years after the start of treatment.

The chances of curing tongue cancer depend heavily on the stage at which the cancer is diagnosed, the size of the tumour and whether metastases have already formed. If the tumour is detected at an early stage, the chances of recovery are very good. The five-year survival rate is up to 80 per cent. The later the tongue cancer is diagnosed, the lower the probability that the tongue cancer will be cured.

In addition to the size of the tumour at the start of treatment, the location is also decisive: the five-year survival rate for tumours on the edge of the tongue is between 35 and 50 per cent. For tumours on the base of the tongue, the rearmost part of the tongue, only 15 to 25 per cent of patients are alive five years after the start of treatment. The general state of health of the person affected also plays a major role in life expectancy.

Symptoms: How do you recognise tongue cancer?

Tongue cancer goes through several stages, from the preliminary stage to the first signs to the fatal final stage. The cancer often remains unrecognised for a long time as it does not cause any pain in the early stages. Here you will find lists of symptoms as well as images of the preliminary stage, initial stage and advanced stage.

Leukoplakia: Possible precursor of tongue cancer

Leukoplakia is a change in the mucous membrane of the tongue: Cornifications form on the uppermost layer of the tongue mucosa, which swell due to the moist environment in the mouth and turn white in colour. The result: white patches on the tongue. The causes of leukoplakia are injuries to the mucous membrane, poor oral hygiene, smoking, alcohol consumption, an unhealthy diet and viral or fungal infections.

Causes: Where does tongue cancer come from?

The exact causes of tongue cancer have not yet been clarified. However, there are a number of risk factors that favour the development of cancer:

• Smoking (cigarettes or e-cigarettes)
• Frequent alcohol consumption (especially high-proof alcohol in combination with tobacco consumption)
• Infection with human papillomavirus (HPV), Eppstein-Barr virus and other viruses
• Poor oral hygiene
• Chronic inflammation of the mucous membranes
• Inflammation at the edge of the tongue due to ill-fitting dentures
• Unbalanced diet with nitrite-containing foods (e.g. sausage and cured meat)

Diagnosis: Choice of doctor for tongue cancer

If you suspect you have tongue cancer, you should have a medical check-up as soon as possible. After all, the chances of recovery are much better if you start treatment as early as possible.

Which doctor for tongue cancer?

The first port of call is your family doctor. During the initial examination, a tissue sample will be taken from the affected area to determine whether it is actually a tumour or not. If necessary, your dermatologist d will refer you to an ENT specialist or oncologist - a cancer specialist. In addition, imaging procedures such as computer tomography (CT), magnetic resonance imaging (MRI), ultrasound and X-rays can be used to determine the severity of the tumour. However, blood tests do not provide any information about a possible tongue cancer.

Treatment of tongue cancer

The treatment depends on how advanced the tongue cancer is, where it is located and whether metastases have already formed. Here we only briefly describe the possible treatment methods. Further information and details on the side effects of radiotherapy, immunotherapy and chemotherapy can be found in our main article on oral cavity cancer. The German Cancer Aid's Blue Guide and the oral cavity cancer patient guidelines are even more comprehensive. There you will also find important information about patients' rights.

Tongue cancer is usually treated with surgery to remove the tumour. In order to prevent a recurrence, radiotherapy, immunotherapy or chemotherapy or a combination of these methods can then be used. In some cases, tongue cancer tumours cannot be removed surgically due to their location or size. A combination of radiotherapy and chemotherapy is then usually used.

The treatment is followed by a stay in a rehabilitation clinic and regular follow-up checks in order to detect a possible recurrence - a new formation of the tumour - at an early stage.

Surgery for tongue cancer

The aim of the operation is to completely remove the tumour from the tongue while preserving tongue function as much as possible. This is often relatively easy to achieve in the front part of the tongue. More complex procedures are required for tongue cancer on the back part of the tongue. During the operation, the surgeon often removes part of the healthy tissue as well as the tumour tissue, as there may be small, invisible outgrowths around the tumour. If metastases have already formed in the lymph nodes of the neck or are suspected, the surgeon will also remove these. The operation can be performed using a laser.

If large parts of the tongue are removed during surgery and this could impair speech, chewing or swallowing function, the surgeons reconstruct the tongue to restore its original shape. To do this, they remove tissue from another part of the body - such as the forearm - and reattach it to the tongue. In this way, function and appearance can be preserved. However, those affected must be prepared to get used to the new tongue first, which can be a months-long process.

Prophylaxis: How you can prevent tongue cancer

Even if it is not yet clear what is ultimately the decisive factor for the development of cancer, you can eliminate some of the risk factors and thus ensure that the likelihood of developing tongue cancer is significantly reduced.

Stop smoking and drinking alcohol

Excessive alcohol and tobacco consumption is the number one risk factor for oral cavity cancer. People who smoke and regularly consume high-proof alcohol are 30 times more likely to develop cancer of the oral cavity than non-smokers who do not drink regularly. Therefore, the most effective protection against tongue cancer is to stop smoking and drinking. This will also make you less susceptible to all other types of oral diseases - including tooth decay and periodontitis. Your liver and lungs will also thank you if you switch to a healthy lifestyle.

Regular check-ups

As tongue cancer is often detected "by chance" by the dentist, it is important that you attend regular check-ups. After all, if tongue cancer wants to spread in your mouth, it will have a much worse chance if you discover it at an early stage. Some dental practices also offer a special early detection examination.

Important: If you wear dentures, you should also have them checked regularly to make sure they fit properly and have them relined if necessary. This will help you avoid pressure points and skin irritation, which can become inflamed and are also a risk factor for tongue cancer.

Examine your tongue regularly

After brushing your teeth, simply stick your tongue out wide and examine it from all sides for any abnormalities. This could be stains, discolouration or growths, for example. Move your tongue to the left and right so that you can inspect the sides. Finally, lift the tongue so that you can also examine the underside.